System overview

The Sefia Cell Processing System is an automated and functionally-closed technology developed for Cell Processing when manufacturing Cell Therapy products. It consists of the Sefia S-1000 platform, dedicated software protocols, and cell processing kits. Use combinations of these protocols and kits for multiple cell processing steps such as washing, concentration, and final formulation.

Sefia S-1000 overview

Product #16000

An adaptive platform for your Cell Processing workflows.

Key features

  • Fast processing of large volumes through innovative continuous-flow centrifugation technology.
  • Smart process control via an automated, closed, and sensor-controlled system.
  • Intuitive user guidance through a responsive interface and user-friendly design.
  • Workflow automation via sequential protocols.

Technical specifications

Feature Description
Core
technology
• Centrifugation technology and a peristaltic pump for continuous flow rates up to 10 L/h.
• Four stopcocks for up to eight fluid pathways.
• Optical sensors for air bubble and air level detection.
• Pressure monitoring sensors.
• Electric motor for centrifugation up to 1600 g.
• Four bag weight sensors (max. 10 kg per bag).
• Peltier modules for temperature control between +4 and +40°C.
Processing
capacity
• Initial: 50 mL to >10 L (kit and protocol dependent).
• Final: >8 mL
Traceability • Barcode reader and printer.
• Data management with PDF reports and procedural graphs.
User
interface
Color touchscreen with an intuitive user graphical interface (GUI).
Software • Compatible with Sefia protocol software only.
• Windows 7 and Bioprocessing Application Software (BPAS).
Connectivity Five USB slots and two ethernet ports.
Dimensions W: 74 cm, L: 51 cm, H: 91 cm (29” x 20” x 36”), 45 kg (99 lbs)
Power 1000 W, 100-240 VAC, 50/60 Hz

Safety and compliance

The Sefia S-1000 is a laboratory instrument with the CE mark intended for Cell Therapy manufacturing in good automated manufacturing practice (GAMP) compliant environments. It is compliant with IEC-61010, IEC-61326, and IEC-62304 standards. For investigational use only.

Storage requirements

  Operation Storage and transport
Temperature +7 to +27°C 0 to +50°C
Relative humidity 30 to 75 %, non-condensing 20 to 75 %, non-condensing